SSRI & SSNRI Antidepressants sid

SSRI & SSNRI Antidepressants side-effects, neurological damage
Selective Serotonin / Nor-Epinehrine Re-Uptake Inhibitors

Go to Introduction Antidepressants Negative personality, perception & physical changes
Go to Antidepressant Casualties in the Media Aggression, Homicide, Suicide & Self-Harm
Go to Recent Media Articles (SSRI) Antidepressants Pharmaceutical & FDA Fraud in 2004

Tardive Dyskinesia/Dystonia, Parkinsonism & Akathisia
SSRI & SSNRI antidepressants induced side-effects (Iatrogenic Extrapyramidal Symptoms) are
recognized to be similar to Neuroleptic (anti-psychotic) induced side-effects. These side-effects are known as Tardive Dyskinesia/Dystonia (severe body movement disorder, mostly permanent), Parkinsonism (a sign of future Parkinson's disease) and Akathisia (a Neurological driven severe mania/agitation that can lead to suicidality, suicide attempts, self-harm & suicide). It is well documented in the medical literature that these neuroleptic induced side-effects refer to damage at dopaminergic neurons in the "motor system" of the
"Basal Ganglia", a structure deep in the "Limbic System" of the brain. 1, 2, 3, 4, http://www.emedicine.com/EMERG/topic338.htm (scroll down)

Serotonin Syndrome
The Serotonin Syndrome is a potentially lethal condition caused by excessive serotonergic activity. It is a very dangerous and a potentially fatal side effect of the serotonergic enhancing drugs such as SSRI & SSNRI antidepressants and is diagnosed by the presence of at least 3 of 10 symptoms: mental status changes (confusion, hypomania), agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever. This "hyperserotonergic" toxic condition requires heightened clinical awareness in order to prevent, recognize, and treat the condition promptly. Promptness is vital because, as we just mentioned, the serotonin syndrome can be fatal and death from this side effect can come very rapidly. The Serotonin syndrome is brought on by excessive levels of serotonin and is difficult to distinguish from the "Neuroleptic Malignant Syndrome" because the symptoms are so similar. The "Neuroleptic Malignant Syndrome" is a serious condition brought on by the use of neuroleptic drugs (anti-psychotics).
Source: Prozac: Panacea or Pandora? by Dr Ann Blake Tracy http://members.aol.com/atracyphd/syndrome.htm
Source: Journal of Clinical Psychiatry

Antidepressant induced neurological and/or physical toxicity (body and/or brain damage) either as a result of prolonged inhibition of P450-2D6 liver-enzymes, or as a result of impairing serotonin metabolism, can take on many forms as described below. A few examples are: Hyperserotonemia, such as the lifethreatening condition the Serotonin Syndrome, Epileptiform Discharges, Epileptic Seizures and/or Epilepsy, Hypoglycaemia/Hyperglycemia (Low/Elevated Blood Sugar Imbalance), Stroke/Hemorrhagic Syndromes, Frontal Lobe Syndrome, Tardive Dyskinesia/Dystonia, Parkinsonism, Akathisia, Mania, etc...

MEDICAL REPORTS OF SSRI/SSNRI ANTIDEPRESSANT INDUCED (IATROGENIC) SEVERE SYMPTOMS:

Go to: Newborn Baby (Neonatal) Neurological Damage & Withdrawal
Go to: General Physical & Mental Side-Effects
Go to: Body Movement Disorders (Dystonia) & Parkinsonism (future Parkinson's disease)
Go to: Akathisia (neurological driven agitation), Mania & Restless Legs Syndrome
Go to: Serotonin Syndrome, Neuroleptic Malignant Syndrome
Go to: Blood/Organ Diseases, Stroke, Hemorrhage, TIA, Tumours & Bleedings
Go to: Hepato Toxicity (Liver Damage)
Go to: Cardiovascular Toxicity (Heart Damage) & Neurological Toxicity (Brain Damage)
Go to: Epileptiform Activity, Epilepsy, Seizures, REM Sleep/Memory/EEG Problems, Sleepwalking

Go to: Hypoglycemia (low blood sugar), Hyperglycemia (high blood sugar, Diabetes)
Go to: Urinary Incontinence, Dermatologic (Skin) Problems, Ocular (Eyes) Disturbances
Go to: Pain & Numbness, Swellings, Sexual (Organ) Problems, Hormonal Imbalances
Go to: Hyponatremia & Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)
Go to: (Suicide Overdose)-Toxicity & Death
Go to: Suicide, Suicidality, Suicide Attempts & Self-Harm
Go to: Mental State, Perceptual, Emotional & Psychological Changes
Go to: Mental & Physical Side-Effects of Withdrawal/Discontinuation
Go to: Other Observations & Complications: Case Reports, Reviews & Studies

Medical reports, side-effects: HYPOGLYCEMIA (Low blood sugar), HYPERGLYCEMIA (High blood sugar, diabetes)


2004	04/00	Animal Study	Hyperglycemia induced by acute central fluoxetine (Prozac) administration
2003	07/00	Case/Review	Hypertriglyceridemia, Acute Pancreatitis & Diabetic Ketoacidosis with Mirtazapine
2003	06/00	Case/Review	Zoloft/Lustral-induced Hyperglycemia: case report
2001	11/00	Case/Review	Sertraline-induced Hypoglycemia
2001	01/00	Animal Study	Fluoxetine (Prozac) caused significant hyperglycemia after injection into the blood...
2000	03/00	Case/Review	Loss of Hypoglycemia Awareness in Diabetic Adolescent during Fluoxetine therapy
1999	10/15	Animal Study	SSRI's Fluoxetine (Prozac) & fluvoxamine (Luvox) induced hyperglycemia...
1999	04/00	Case/Review	Hypoglycemia associated with high doses of sertraline & sulphonylurea compound
1997	11/00	Case/Review	Baby Prozac (withdrawal) side-effects: Hyperglycaemia (High blood sugar, Diabetes)
1996	11/00	No Abstract	Suggestive episodes of hypoglycemia related to fluoxetine (Prozac, Sarafem)
1996	11/01	Case/Review	Hyperglycemia Associated with Paroxetine
1996	03/00	No Abstract	Hypoglycemia associated with the use of fluoxetine (Prozac)

Medical reports: URINARY INCONTINENCE, DERMATOLOGIC (Skin) PROBLEMS, OCULAR (Eyes) DISTURBANCES


2003	05/00	Case/Review	Bupropion-induced Rash with Eosinophilia & Systemic Symptoms Syndrome
2002	09/00	Case/Review	Mirtazapine associated with Significant Weight Gain
2002	06/00	Case/Review	Generalized Pustular & Erythrodermic Psoriasis associated with Bupropion
2002	06/00	Case/Review	Zoloft/Lustral-induced Urinary Incontinence
2002	05/00	Case/Review	Urinary Incontinence with mirtazapine
2002	04/00	Case/Review	Two cases of rash induced specifically by paroxetine
2001	00/00	Case/Review	Bruxism (Teeth Grinding)
2001	12/00	Case/Review	Photopigmentation
2001	07/00	Case/Review	Venlafaxine-Induced Hair Loss
2001	06/07	Case/Review	Cutaneous Lesions during SSRI's therapy: 2 cases
2001	05/00	Case/Review	Mitrazapine-associated Palinopsia
2001	03/00	Case/Review	Cutaneous Vasculitis (severe dermatologic side-effects) Induced by Paroxetine
2000	12/00	Case/Review	Serotonergic antidepressants and Urinary Incontinence
2000	06/00	No abstract	Acute Angle Closure Glaucoma presenting in a Young Patient after paroxetine
2000	04/02	Case/Review	Severe Alopecia (massive hair loss) due to Paxil/Seroxat (paroxetine) therapy
1999	10/00	Case/Review	Effexor-induced Bruxism (Teeth Grinding)
1999	07/08	Case/Review	Hair loss associated with paroxetine treatment: a case report
1998	03/04	Case/Review	Increased Ocular Pressure in 2 patients treated with venlafaxine
1997	05/10	Case/Review	Acute angle closure glaucoma associated with paroxetine
1997	03/00	Case/Review	Bilateral acute angle closure glaucoma after administration of paroxetine
1996	11/00	Case/Review	Paxil/Seroxat (paroxetine) induced bruxism (teethgrinding)

Medical reports: PAIN & NUMBNESS, SWELLINGS, SEXUAL (ORGAN) PROBLEMS, HORMONAL IMBALANCES


2002	00/00	Case/Study	Abstract: Sexual Dysfunction & Newer Antidepressants
2002	10/00	Case/Review	Effexor (& other antidepressants) -induced Sexual Dysfunction
2002	10/00	Case/Review	Antidepressant-induced sexual dysfunction
2002	09/00	Case/Review	Long-term side effects of newer-generation SSRI antidepressants
2002	07/00	Case/Review	Paxil/Seroxat (paroxetine)-induced vaginal anaesthesia
2002	05/00	Case/Review	Effexor/Efexor (venlafaxine)-associated Vaginal Bleeding
2002	04/00	Case/Review	Remeron (mirtazapine) associated with Higher Rates for Risk of Sexual Dysfunction
2002	04/00	Case/Review	Celexa/Cipramil (citalopram)-induced Priapism
2001	00/00	Case/Review	Incidence of sexual dysfunction associated with antidepressant agents: SSRI's
2001	12/00	Case/Review	Remeron-induced Arthralgia (joint pain, stiffness) & Myalgia (muscle pain, viral)
2001	08/00	Case/Review	Flushing/Return of Hot Flashes in Menopausal Woman Taking Effexor (venlafaxine)
2001	06/07	Case/Review	Cutaneous adverse effects: painful papular & purpuric erythema with Paxil/Seroxat
2000	00/00	Case/Review	Abstract: SSRIs & Sexual Dysfunction (Paxil, Zoloft, Effexor)
2000	00/00	Case/Review	Prozac (fluoxetine)-induced Anaesthesia of Vagina and Nipples
2000	10/00	Case/Review	Sexual Dysfunctions induced by Celexa/Cipramil & SSRI's
2000	09/00	Case/Review	Reduced Testosterone Level in Effexor (venlafaxine) treated patient
2000	04/00	Case/Review	Effexor (venlafaxine)-induced Painful Ejaculation
2000	04/00	Case/Review	Abstract: SSRIs & Sexual Dysfunction (Paxil, Zoloft, Effexor)
2000	03/00	Case/Review	Prozac/Sarafem (fluoxetine) and grossly swollen muscles & oedematous
1999	05/00	Case/Review	Paxil/Seroxat (paroxetine)-induced Anorgasmia in 41-year-old Caucasian woman
1998	06/00	Case/Review	Sexual Dysfunction associated with Remeron/Remergil (mirtazapine): a case report
1997	03/00	Case/Review	Celexa/Cipramil (citalopram)-induced Clitoral Priapism
1996	05/00	Case/Review	Priapism (painful persistent erection of penis) caused by Paxil/Seroxat (paroxetine)
1996	01/00	Case/Review	Celexa/Cipramil (citalopram)-induced Anorgasmia

Medical reports, side-effects: HYPONATREMIA & SIADH


2004	02/09	Case/Study	Paroxetine-induced hyponatremia in older adults: a 12-week prospective study
2004	01/16	Case/Review	Severe Symptomatic Hyponatremia
2003	00/00	Case/Review	Mirtazapine-induced Hyponatraemia
2003	09/00	Case/Study	Hyponatremia in the elderly due to inappropriate secretion of antidiuretic hormone
2003	06/15	Case/Review	Hyponatraemia with SSRI's
2002	00/00	Case/Review	Paroxetine Associated Hepatotoxicity: Report of 3 Cases & Review of the Literature
2002	00/00	Case/Review	Severe Hyponatraemia with Coma & Seizure
2002	10/00	Case/Review	Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)
2002	03/00	Case/Review	Hyponatremia & SIADH associated with Sertraline and Fluoxetine: a case report
2002	03/00	Case/Review	Hyponatremia associated with Zoloft/Lustral & Prozac/Sarafem
2002	03/00	Case/Review	Hyponatraemia in elderly psychiatric patients treated with SSRIs & Effexor
2001	05/00	Case/Review	Venlafaxine has a stronger association with Hyponatraemia
2001	02/00	Case/Review	Severe Symptomatic Hyponatremia
2000	03/02	Case/Review	SIADH with Epileptic Seizures and Coma in fluoxetine therapy
1999	00/00	Case/Review	Severe life-threatening hyponatremia during paroxetine therapy
1999	03/00	Case/Review	Severe Hyponatremia during treatment with fluoxetine
1998	06/00	Case/Review	Sertraline-assoc. Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
1998	01/00	Case/Review	Hyponatremia with venlafaxine
1998	01/00	Case/Review	Hyponatremia associated with paroxetine
1997	00/00	Case/Review	Syndrome of Inappropriate Secretion of Antidiuretic Hormone in 2 elderly women
1997	06/00	Case/Review	Syndrome of Inappropriate ADH Secretion (SIADH) attributed to venlafaxine
1996	11/25	Case/Review	SSRI's: Hyponatremia by Schwartz-Bartter Syndrome
1996	09/01	Case/Review	Hyponatremia & SIADH associated with SSRI's: a review of spontaneous reports
1996	07/00	Case/Review	The role of sertraline in a patient with Recurrent Hyponatremia
1996	04/00	Case/Review	Fluoxetine: Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)

Medical reports, side-effects: SUICIDE, SUICIDALITY, SUICIDE ATTEMTPS & SELF-HARM


2004	09/14	FDA US	Antidepressant "BLACK BOX WARNING" On Suicidality Risk Recommended
2004	08/26	FDA US	New Warning Required: Antidepressants Induced Suicide in Children & Adults
2004	08/20	FDA US	FDA Update Review SSRI's: data suggestive of increased suicidality risk
2004	06/08	HealthCanada	ZYBAN WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	06/03	Health Canada	Stronger warnings for SSRI's & other anti-depressants
2004	05/26	HealthCanada	REMERON WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	05/26	HealthCanada	ZOLOFT WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	05/26	HealthCanada	CELEXA WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	05/26	HealthCanada	EFFEXOR WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	05/18	HealthCanada	PROZAC WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	05/18	HealthCanada	PAXIL WARNING: Risk of suicide, self-harm, behavioural/emotional changes
2004	04/23	EMEA/EUROPE	CPMP/EMEA warning EUROPE: Paxil should not be used in children & adolescents
2004	03/22	FDA US	FDA: Cautions for Use of Antidepressants in Adults & Children
2004	03/22	FDA US	FDA: Worsening Depression & Suicidality with Antidepressant Medications
2004	03/11	TGA AUS	TGA: Use of SSRI antidepressants in children and adolescents
2004	02/03	FDA US	Antidepressant Strengthened Warnings Pediatric Suicidality Risk
2003	00/00	Case/Review	Paxil can cause some individuals to commit homicide and/or suicide
2003	12/10	MHRA/CSM UK	SSRI antidepressants not for under 18 years in United Kingdom / MHRA site
2003	10/00	Case/Study	Suicide Attempts in Clinical Trials with SSRI's in (MDD) Children
2003	09/00	Case/Review	Antidepressants (SSRI's) and suicide: risk-benefit conundrums
2003	09/02	Case/Review	Paxil: increased risk of suicidal thoughts, suicide attempts & self-harm in children
2003	08/22	Wyeth	Effexor/Efexor induces suicidal/homicidal behaviour in children
2003	06/15	Case/Review	Paxil not for under 18-studies showing higher rates suicidal thoughts & behaviour
2003	04/00	Case/Study	Clinical Study Dr David Healy: Lines of evidence on Risks of suicide with SSRIs
2001	03/00	Case/Study	Treatment-Emergent Behavioural Side-Effects in adults with learning disabilities
2001	01/00	No abstract	PAXIL AND SELF-SCRATCHING
2000	06/13	Case/Study	Occurrence of Deliberate Self-Harm highest with Fluoxetine (Prozac/Sarafem)
2000	05/30	Clinical Trial	Use of Sertraline (Zoloft) Linked to Suicidality
1999	12/00	Case/Review	Deliberate Self-poisoning following Luvox/Fevarin-Neuroleptics combination
1994	02/00	Case/Review	Fluoxetine and Violent Death in Maryland: violent methods in fluoxetine suicides
1995	00/00	Case/Review	Fluoxetine: increased suicidal ideation and/or agitation have been reported
1992	11/00	Case/Review	Irritability, Self-Damage by Cutting & Violent Intense Suicidal, Paranoid Ideation
1991	12/00	Case/Review	Serious suicide attempts by 3 patients during treatment Fluoxetine: Akathisia
1991	03/00	Case/Review	Emergence of Self-destructive phenomena in children during Prozac treatment
1990	02/00	Case/Review	Emergence of Intense Suicidal Preoccupation during Prozac (Sarafem) treatment

Medical reports, side-effects: MENTAL STATE, PERCEPTUAL, EMOTIONAL & PSYCHOLOGICAL CHANGES


2004	03/00	Case/Review	Hallucinations with zolpidem and fluoxetine in an impaired driver
2003	10/00	No abstract	Visual and auditory hallucinations with excessive intake of paroxetine
2003	07/00	Case/Review	A case report of Paranoid Delusion with venlafaxine use
2003	07/22	Case/Review	Bupropion: Tremors, Agitation, Confusion, Insomnia & Rash
2003	04/00	Case/Review	Venlafaxine and Increased Aggression in a female with autism
2002	09/00	Case/Review	Panic Attacks
2002	04/00	No abstract	Pathologic laughter associated with paroxetine treatment
2002	01/14	Case/Review	Acute Psychosis after Administration of Bupropion Hydrochloride (Zyban)
2001	00/00	Case/Review	An Organic Psychosis due to a venlafaxine-propafenone interaction
2001	02/00	Case/Review	Visual hallucination and tremor induced by sertraline and oxycodone
2000	09/00	Case/Review	Melancholic Depression during concurrent olanzapine and fluoxetine
2000	07/00	Case/Review	Occurrence of Mirtazapine-induced Delirium in organic brain disorder
2000	07/08	Case/Review	Onset of psychotic symptoms & pseudoneurotic schizophrenia with paroxetine
2000	05/06	Case/Review	Sertraline-induced Panic Attacks
2000	02/07	Case/Review	Zoloft/Lustral: Wrong Drug for Panic
1999	00/00	Case/Review	Postoperative delirium indicating an adverse drug interaction involving paroxetine
1998	04/01	Case/Review	Hallucinations as a Side Effect of "Venlafaxine"(Effexor) Related Link
1997	00/00	Case/Review	Toxic Delirium & general Tonic-Clonic Seizure with Prozac & low dose Trazodone
1997	11/00	Case/Review	Psychosis during chronic levodopa therapy triggered by Mirtazapine
1997	03/00	Case/Review	Sertraline and Psychotic Symptoms: a case series
1996	00/00	Case/Review	Nightmares and hallucinations after long-term intake of tramadol & Paxil/Seroxat
1993	12/00	Case/Review	Acute Hyperkinetic Delirium during fluoxetine treatment. A case report
1992	12/00	Case/Review	Severe extra pyramidal side effects associated with paroxetine
1992	07/00	Case/Study	Fluoxetine in autistic disorder: restlessness, hyperactivity, agitation, insomnia...
1982	09/00	Case/Review	Perceptual Changes with Bupropion

Medical reports, side-effects: MENTAL & PHYSICAL SIDE EFFECTS OF WITHDRAWAL/DISCONTINUATION


2004	02/00	Case/Review	A Case Report of Mania Related to Discontinuation of Wellbutrin (bupropion)
2003	12/00	Case/Review	Premature Ejaculation associated with Celexa (Cipramil, citalopram) withdrawal
2003	07/12	Case/Review	Withdrawal symptoms in Baby after exposure to venlafaxine during pregnancy
2003	07/08	Case/Review	Severe Headache with venlafaxine withdrawal
2003	05/00	Case/Review	Shock-like Sensations during Venlafaxine Withdrawal
2003	05/00	Case/Review	Antidepressant withdrawal-induced Mania in patients with mood disorders
2002	00/00	Case/Review	Venlafaxine -Long Term Adverse Effects
2002	11/00	Case/Review	Paxil/Seroxat usage patterns as risk factors for hospitalization
2002	07/00	Case/Review	Discontinuation/Withdrawal Reactions associated with Effexor (venlafaxine)
2002	06/00	Case/Review	Delirium during Withdrawal of Effexor
2002	02/02	Brit.Med.J.	Withdrawal from Paxil (Seroxat, paroxetine) is Severe Warns FDA
2001	00/00	Case/Review	SSRI-Antidepressant Discontinuation Syndromes
2001	07/00	Case/Review	Withdrawal Reactions with Effexor (venlafaxine) presenting as stroke
2001	04/11	Medscape	Antidepressant Discontinuation Syndromes: Common & Under-Recognised
2000	05/00	Case/Review	SSRI Discontinuation Syndrome/Withdrawal: proposed diagnostic criteria
2000	04/15	Case/Review	Persistent Adverse Neurological Effects following SSRI Discontinuation
2000	04/01	Case/Study	Altered Serotonergic Function [as in withdrawal] & Aggressive Behavior
2000	03/00	Case/Review	Discontinuation/Withdrawal Reactions associated with Effexor (venlafaxine)
1999	07/00	Case/Review	Selective serotonin reuptake inhibitor Discontinuation/Withdrawal Symptoms
1998	11/09	Case/Review	Antidepressant Discontinuation-Related Mania also in Bipolar Depression
1998	10/00	No Abstract	Discontinuation Symptoms and SSRIs
1998	09/19	Case/Review	Discontinuation/Withdrawal Reactions associated with Effexor (venlafaxine)
1998	04/00	Case/Review	Discontinuation/Withdrawal Reactions associated with Effexor (venlafaxine)
1998	02/00	Case/Review	Akathisia in withdrawal reactions Effexor (venlafaxine)
1997	12/00	Case/Review	Discontinuation/Withdrawal Reactions associated with Effexor (venlafaxine)
1996	10/00	Case/Review	Serotonin reuptake inhibitor withdrawal
1996	03/00	Case/Review	Sertraline Withdrawal in two brothers: a case report
1995	01/00	Case/Review	Reversible Delirium after discontinuation of Prozac (fluoxetine)

Medical reports, side-effects: (SUICIDE OVERDOSE)-TOXICITY & DEATH


2003	12/00	Case/Review	Fatality related to a 30-g venlafaxine overdose
2003	11/00	Case/Review	Bupropion-overdose: Patient suffered from Prolonged Symptoms & Seizures
2003	08/00	Case/Review	Cardiotoxicity & Late Onset Seizures with overdose
2003	07/08	Case/Review	Bupropion overdose: QTc Prolongation and its clinical significance
2003	05/00	Case/Review	Effexor/Efexor is more likely to cause serotonin toxicity in overdose
2002	11/00	Case/Review	Cardiotoxicity following Wellbutrin/Zyban overdose
2002	10/04	Case/Review	Deaths, Arrhythmias & Seizures in Effexor (venlafaxine) overdose
2002	08/00	Case/Review	Venlafaxine Poisoning complicated by a late rise in creatine kinase
2002	07/00	Case/Review	Postmortem Concentrations of Citalopram
2002	01/11	Case/Review	Toxicity of Wellbutrin/Zyban in deliberate self-poisoning in adults
2002	01/00	Case/Review	Wellbutrin/Zyban overdose: Severe Cardiac Arrhythmias, Hallucinations & Seizures
2002	01/00	Case/Review	Wellbutrin/Zyban: Significant Neurological & Cardiovascular Toxicity in overdose
2001	10/00	Case/Review	Determined to be incidental finding to ultimate Cause of Death in 11 Cases
2001	05/06	Case/Review	QTc Interval Prolongation associated with overdose
2001	04/00	Case/Review	14-year-old boy who ingested 1.5 to 3 g of Bupropion in a Suicide Attempt
2001	01/16	Case/Review	Conduction Disturbances Associated with Venlafaxine-overdose
2000	10/00	Case/Review	An unusual multiple drug Fatal Intoxication case involving citalopram
2000	09/00	Case/Review	Death from asthma associated with sertraline overdose
2000	07/00	Case/Review	Suicide Attempt Overdose: Severe Sinus Bradycardia; Pacemaker
2000	05/00	Case/Review	Antidepressants can result in Toxicity and Death through serotonergic excess
2000	05/00	No abstract	Association of paroxetine with suicide attempt in obsessive-compulsive disorder
2000	05/00	Case/Review	Sertraline can result in Toxicity and Death through serotonergic excess
2000	04/00	Case/Review	Child, 9; liver cytochrome P-450 2D6 deficiency; Prozac-related death
1999	07/08	Case/Review	A young nurse commits suicide with doxepin and paroxetine (Paxil/Seroxat)
1999	05/00	Case/Review	Effexor/Efexor: Significant Cardiovascular & Neurological Toxicity in overdose
1998	11/00	Case/Review	Autopsy cases in which Citalopram (Toxicity) alone was the Cause of Death
1998	09/10	Case/Review	Tonic Clonic Seizures & Tachycardia induced by fluoxetine (Prozac) overdose
1998	06/00	Case/Review	Paxil suicide attempt by 83-year-old: hyponatremia, confusion, muscle spasms...
1997	00/00	Case/Review	Fatal Bupropion-overdose
1997	02/00	Case/Review	Seizure resulting from a venlafaxine overdose
1996	07/08	Case/Review	Two Fatal Cases of Venlafaxine Poisoning
1995	00/00	Case/Review	A case report of venlafaxine-overdose Toxicity
1995	08/00	Case/Review	Seizure after isolated fluoxetine-overdose
1994	03/00	Case/Review	Bupropion-overdose: Grand Mal Seizures & Sinus Tachycardia
1991	09/00	Case/Review	Unexpected Deaths in depressed medical inpatients treated with Fluoxetine
1989	00/00	Case/Review	Fluoxetine-overdose: Flu-like Symptoms, Urticaria & Angioedema
1982	03/00	AnimalStudy	High dose toxicity in Dogs: Severe Convulsive Attacks, Sinus Tachycardia & Death

OTHER OBSERVATIONS & COMPLICATIONS: CASE REPORTS, REVIEWS & STUDIES


2004	07/14	FDA Warning	FDA warning Cipramil (citalopram): Aluminum Toxicity in interaction with linezolid
2004	03/00	Case/Review	Bupropion and its active metabolites are present in breast milk
2004	02/00	Case/Review	SSRI's not so selective: Increased Brain GABA Concentrations
2003	10/00	Case/Review	Adverse event reporting with SSRI antidepressants - The Weber effect
2002	12/00	Case/Review	Observational study Sertraline: over 100 different unlabelled adverse events
2002	10/00	Case/Study	Risk factors for falls during Paxil/Seroxat treatment of late-life depression
2002	09/00	Case/Review	Pharmacologic management of SSRI-induced side effects: survey of psychiatrists
2002	09/03	Case/Review	Drug safety without borders: Concerns about Wellbutrin/Zyban
2002	06/03	Case/Review	Perhexiline Toxicity related to Citalopram use
2002	05/00	AnimalStudy	Impaired Spatial Learning in the Morris water maze induced by SSRI's in rats
2002	02/00	Case/Review	SSRI's & cytochrome P-450 liver enzyme mediated drug-drug interactions: update
2001	02/00	Case/Review	Reversible Galactorrhea & Prolactin Elevation related to fluoxetine use
2000	00/00	Sev. Studies	Iatrogenic (drug induced) side-effects from Antidepressants
1999	03/00	Case/Review	SSRI's Noncompetitively Inhibit Nicotinic Acetylcholine Receptor Function
1998	09/00	Case/Review	SSRI's: differences in inhibition of the cytochrome P450 liver enzyme system
1997	12/21	Moore/Study	Hard to Swallow: Serzone and Effexor
1997	09/00	Case/Review	Excretion of Citalopram in Breast Milk
1997	07/00	Case/Review	Paroxetine and galactorrhea (breasts leaking white fluid - possible cancer when red)
1996	08/12	Case/Review	Placebo Effect Accounts for 50% Improvement in Patients on Antidepressants
1993	00/00	Case/Review	Fluoxetine: Adverse Effects and drug-drug Interactions
1993	11/00	Case/Review	SSRI-associated nocturnal Bruxism (teeth-grinding) in 4 patients
1992	09/00	Case/Review	Effect of SSRI's on cytochrome P450 (CYP2D6) activity in human liver microsomes


Antidepressant Neurological Side-Effects:		Addiction & Withdrawal
Antidepressant Neurological Side-Effects:		Akathisia & Mania (Suicide & Aggression)
Antidepressant Neurological Side-Effects:		Serotonin Syndrome
Antidepressant Neurological Side-Effects:		Toxicity & Brain Damage
Antidepressant Neurological Side-Effects:		"Anecdotal" Reports -Personal Experiences


Antidepressants:		How To Wean/Taper Off
Antidepressants:		How to Survive a Negative Reaction
Antidepressants:		Conquering Depression and Anxiety